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Current Opinions in the Kyoto Cornea Club - I

edited by: S. Kinoshita & Y. Ohashi

Price: € 28.00 / US $ 35.00

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Publication details: Book. 1997. x and 109 pages. Publication date: 1997-08-29. 65 figures of which 12 in full color, and 11 tables. Paperbound.

ISBN: 978-90-6299-138-9 (ISBN 10: 90-6299-138-6; Kugler Publications)

Also available as ebook



During the past two decades, a significant international research exchange has taken place in order to understand the pathobiology of corneal diseases, and to develop more sophisticated treatments. For this purpose, many Japanese cornea specialists have been abroad to the United States, the United Kingdom, etc., to perform collaborative works in basic and clinical cornea research. As a result, many original concepts and thoughts have been produced from Japan, and some of them are now accepted world wide. Further to promote the international exchange of current knowledge and research on corneas in both health and disease, the First Annual Meeting of the Kyoto Cornea Club was held in Kyoto City on December I and 2, 1995. The goal of this meeting was to provide each speaker's updated knowledge that would be of value to all active corneal researchers who are interested in 'state-of-the-art' information from Japan. To achieve this objective fully, 41 selected Japanese cornea specialists registered as active participants in this meeting. James D. Zieske, PhD, from Schepens Eye Research Institute and the Department of Ophthalmology at Harvard Medical School, Boston, MA, USA, and Tadatsugu Taniguchi, PhD, from the Department of Immunology, Faculty of Medicine, Tokyo University, Japan, participated as special guests at this meeting, and both gave plenary lectures.
This volume was created to provide each speaker's current opinions on the subjects they presented at this meeting, and also to provide a scientific reference for cornea research. We hope that the first issue will serve as a useful source of current knowledge and insight on Japanese cornea research. We wish to thank all those whose administrative help and/or assistance has made this issue possible; Takakazu Morita of Santen Pharmaceutical Co. Ltd., Machiko Tsujino of PMSI Japan, Ltd., and Kugler Publications.

Shigeru Kinoshita and Yuichi Ohashi

Table of Contents

Table of Contents

List of Club Members
List of Contributors

Invited lectures

The transcription factors IRF-1 and IRF-2 in the regulation of the interferon system and cell growth
T. Taniguchi

Corneal Epithelial Differentiation
J.D. Zieske


New approaches in dry eye management supplying missing tear components to the ocular surface epithelium
K. Tsubota

New approaches to human ocular surface epithelium: From basic understanding to clinical application
S. Kinoshita

Biology of corneal stromal keratocytes
T. Nishida

Current topics regarding the corneal endothelial cell
M. Sawa

Polymerase chain reaction in viral infections of the cornea
Y. Ohashi

Corneal transplantation and immunosuppressive therapy
A. Kanai


Interaction between t lymphocytes and corneal epithelal cells immunological function of corneal epithelial cells
M. Iwata

The effect of fibrin formation on corneal endothelial cells in vitro: Thrombin and corneal endothelial cell function and morphology
T. Sakamoto and H. Inomata

Mouse keratoepithelioplasty model
Y. Inoue and Y.-F. Yao

HLA-DNA typing in corneal transplantation
J. Shimazaki

Index of authors

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